Phagocytosis and avirulent Treponema pallidum.
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چکیده
منابع مشابه
Phagocytosis and avirulent Treponema pallidum.
SIR-Uptake of avirulent T. pallidum (Nichols strain) was demonstrated in an in vitro system. Motile treponemes were harvested after culture for 7 days in spirolate broth (Izzat, Knox, and Wende, 1971). Non-motile treponemes were also obtained by keeping some of these at 4°C. for 18 hours. Macrophages were obtained from the peritoneal cavity of a rabbit bywashing with 100 ml. Hanks's balanced sa...
متن کاملEffect of gentamicin sulphate on avirulent and virulent Treponema pallidum.
The bactericidal activity of the aminoglycoside gentamicin has been demonstrated against a broad spectrum of bacteria (Jackson and Finland, 1969). This spectrum included Neisseria gonorrhoeae (Waitz and Weinstein, 1969); however, before gentamicin is used for the treatment of gonorrhoea, its effect on Treponema pallidum should be investigated to determine whether it can delay or mask the develo...
متن کاملShape of Treponema pallidum.
Treponema pallidum was found to be not helical, but a flat wave twisted into one to five different planes per cell.
متن کاملMucopolysaccharidase of Treponema pallidum.
Treponema pallidum (Nichols strain) exhibited mucopolysaccharidase activity. Acidic mucopolysaccharides were broken down more rapidly by viable treponemes than by heat-inactivated treponemes or membrane filtrates of treponemal suspensions. Ouchterlony immunodiffusion demonstrated the occurrence of antibodies to the hyaluronidase-like enzyme within syphilitic sera. After intratesticular inoculat...
متن کاملPhagocytosis of Borrelia burgdorferi and Treponema pallidum potentiates innate immune activation and induces gamma interferon production.
We examined the interactions of live and lysed spirochetes with innate immune cells. THP-1 monocytoid cells were activated to comparable extents by live Borrelia burgdorferi and by B. burgdorferi and Treponema pallidum lysates but were poorly activated by live T. pallidum. Because THP-1 cells poorly internalized live spirochetes, we turned to an ex vivo peripheral blood mononuclear cell system ...
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ژورنال
عنوان ژورنال: Sexually Transmitted Infections
سال: 1972
ISSN: 1368-4973
DOI: 10.1136/sti.48.5.402